Leading Researcher in molecular biology of Plasmodium vivax malaria, Molecular Biology and Immunology of Malaria (BMIM), Rene Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-Minas). Ph.D. (1998) Biochemistry and Immunology, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG; Post-Doc (2015) Yerkes National Primate Research Institute, Emory University, Atlanta, GA; Malaria Journal, Academic Editor.

Contact Info

cristiana.brito@fiocruz.br

Office:

IRR, FIOCRUZ-Minas

Av. Augusto de Lima 1715, 30190-009, Belo Horizonte, MG, Brazil 

Phone: 55-31-33497872

Portuguese: CV: https://lattes.cnpq.br/0553918889655570

English: https://orcid.org/0000-0002-8888-5477   

https://www.webofscience.com/wos/author/record/IWU-5826-2023

Research Interests 

My background is in molecular biology, first in schistosomiasis and in the last 20 years in malaria. My areas of expertise are: heterologous expression systems in bacteria and baculovirus, genetic variability, population genetics and natural selection. My major research topics are Simian malaria, molecular diagnosis of malaria and relapses markers in malaria. In 2015, as a visiting researcher at Emory University  started two new research lines in immunology profiling of malaria in non-human primates and also metabolomics of malaria, particularly relapses in P.vivax-infected patients.

Relevant publications

Complete List of Published Work:  

https://www.webofscience.com/wos/author/record/IWU-5826-2023

MOURIER, TOBIAS; DE ALVARENGA, DENISE ANETE MADUREIRA; KAUSHIK, ABHINAV; DE PINA-COSTA, ANIELLE; DOUVROPOULOU, OLGA; GUAN, QINGTIAN; GUZMÁN-VEGA, FRANCISCO J.; FORRESTER, SARAH; DE ABREU, FILIPE VIEIRA SANTOS; JÚNIOR, CESARE BIANCO; DE SOUZA JUNIOR, JULIO CESAR; MOREIRA, SILVIA BAHADIAN; HIRANO, ZELINDA MARIA BRAGA; PISSINATTI, ALCIDES; FERREIRA-DA-CRUZ, MARIA DE FÁTIMA; DE OLIVEIRA, RICARDO LOURENÇO; AROLD, STEFAN T.; JEFFARES, DANIEL C.; BRASIL, PATRÍCIA; DE BRITO, CRISTIANA FERREIRA ALVES; CULLETON, RICHARD; DANIEL-RIBEIRO, CLÁUDIO TADEU; PAIN, ARNAB. The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching. BMC BIOLOGY, v.19, p.219 - 236, 2021

 DE ALVARENGA, DENISE ANETE MADUREIRA; CULLETON, R.; PINA-COSTA, A.; RODRIGUES, D. F.; BIANCO JUNIOR, C.; SILVA, S.; NUNES, A. J. D.; SOUZA-JUNIOR, J. C.; HIRANO, Z. M. B.; MOREIRA, SILVIA B.; PISSINATTI, A.; ABREU, F. V. S.; AREAS, A. L. L.; LOURENCO-DE-OLIVEIRA, R.; ZALIS, M. G.; Cruz, MFF; BRASIL, P.; DANIEL-RIBEIRO, C. T.; Brito, Cristiana FA
An assay for the identification of Plasmodium simium infection for diagnosis of zoonotic malaria in the Brazilian Atlantic Forest. Scientific Reports, v.8, p.86, 2018.

Nóbrega de Sousa, Taís; Carvalho, Luzia Helena; BRITO, C. F. A.
Worldwide Genetic Variability of the Duffy Binding Protein: Insights into Plasmodium vivax Vaccine Development. Plos One, v.6, p.e22944 - , 2011.

BRASIL, PATRÍCIA; ZALIS, MARIANO GUSTAVO; DE PINA-COSTA, ANIELLE; SIQUEIRA, ANDRE MACHADO; JÚNIOR, CESARE BIANCO; SILVA, SIDNEI; AREAS, ANDRÉ LUIZ LISBOA; PELAJO-MACHADO, MARCELO; DE ALVARENGA, DENISE ANETE MADUREIRA; DA SILVA SANTELLI, ANA CAROLINA FARIA; ALBUQUERQUE, HERMANO GOMES; CRAVO, PEDRO; SANTOS DE ABREU, FILIPE VIEIRA; PETERKA, CASSIO LEONEL; ZANINI, GRAZIELA MARIA; SUÁREZ MUTIS, MARTHA CECILIA; PISSINATTI, ALCIDES; Lourenço-de-Oliveira R; BRITO, C. F. A.; DE FÁTIMA FERREIRA-DA-CRUZ, MARIA; CULLETON, RICHARD; DANIEL-RIBEIRO, CLÁUDIO TADEU
Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation. Lancet Global Health, v.109, p.1 - , 2017.Ceravolo IP, Sanchez BA, Sousa TN, Guerra BM, Soares IS, Braga EM, McHenry AM, Adams JH, Brito CF, Carvalho LH. Naturally acquired inhibitory antibodies to Plasmodium vivax Duffy binding protein are short-lived and     allele-specific following a single malaria infection. Clin Exp Immunol.; 156(3):502-10, 2009;  

 TENDLER, M.; BRITO, C. F. A.; VILAR, M.M.; SERRAFREIRE, N.; DIOGO, C.; ALMEIDA, M.; DELBEM, A.C.; da SILVA, J.F; SAVINO, W.; GARRAT, R.; KATZ, N.; SIMPSON, A. J. G.
A Schistosoma mansoni fatty acid-binding protein, Sm14, is the potential basis of a dual-purpose anti-helminth vaccine. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.93, p.269 - 273, 1996.